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| Product Name | MIP-1 alpha, Recombinant, Human (Macrophage Inflammatory Protein 1 alpha, CCL3) |
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| Description | Purity ~96% (SDS-PAGE, HPLC). Macrophage Inflammatory Proteins (MIP) belong to the family of chemotactic cytokines known as chemokines. In humans, there are two major forms, MIP- 1a and MIP-1b that are now officially named CCL3 and CCL4 respectively. Both are major factors produced by macrophages after they are stimulated with bacterial endotoxins. They activate human granulocytes (neutrophils, eosinophils and basophils) which can lead to acute neutrophilic inflammation. They also induce the synthesis and release of other pro-inflammatory cytokines such as interleukin 1(IL-1), IL-6 and TNF-alpha from fibroblasts and macrophages. The genes for CCL3 and CCL4 are both located on human chromosome 17. Source: Recombinant protein corresponding to human MIP-1 alpha, containing 69aa residues, including the four highly conserved cysteine residues present in CC chemokines, expressed in E. coli. Molecular Weight: ~7.8kD (69aa) Applications: Suitable for use in SDS-PAGE. Other applications not tested. Recommended Dilution: Opt |
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| Size | 5ug, 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 360784 |
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| Order / More Info | MIP-1 alpha, Recombinant, Human (Macrophage Inflammatory Protein 1 alpha, CCL3) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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