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| Product Name | CREB, phosphorylated (Ser133) (cAMP Response Element Binding Protein) Blocking Peptide |
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| Description | Transcription factor CREB binds the cyclic AMP response element (CRE) and activates transcription in response to a variety of extracellular signals including neurotransmitters, hormones, membrane depolarization, and growth or neurotrophic factors. Protein kinase A and the calmodulin-dependent protein kinase CaMKII stimulate CREB phosphorylation at Ser133, a key regulatory site controlling transcriptional activity (1,2). Phosphorylation at Ser133 is also mediated by p44/42 MAP kinase, p90RSK, p38 MAP kinase and MSK1 (3-5). CREB appears to play an important role in learning and memory in both flies and mice. Produced by immunizing rabbits with a synthetic phosphopeptide (KLH coupled) corresponding to residues around Ser133 of human CREB. Corresponding antibody, C7915-10, detects endogenous levels of CREB only when phosphorylated at serine 133. Also detects the phosphorylated form of CREB-related protein ATF-1. Species Crossreactivity: Mouse and rat. Applications: Suitable for use in ELIS |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | C7915-10A |
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| Price | |
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| Order / More Info | CREB, phosphorylated (Ser133) (cAMP Response Element Binding Protein) Blocking Peptide from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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