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| Product Name | Dipeptidylpeptidase IV, Recombinant, Human, aa39-766, His-Tag |
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| Description | Purity ~95% (SDS-PAGE). DPP4 is a serine exopeptidase and complex enzyme that is expressed on the surface of most cell types as an intrinsic membrane glycoprotein that cleaves X-proline dipeptides from the N-terminus of polypeptides and plays a role in t-cell activation. DPP4 is associated with intracellular signal transduction, apoptosis and involved in tumor biology. There are at least 63 substrates which can bind specifically to DPP4 enzyme including growth factors, chemokines, neuro peptides. Furthermore, DPP4 plays a major role in glucose metabolism by cleaving incretins such as glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1). Source: Recombinant protein corresponding to human DPP4, a single, glycosylated polypeptide chain containing 746aa (aa39-766), fused to His-tag at C-terminal, expressed in High-5 cells. Molecular Weight: ~86.4kD Biological Activity: >20units/mg Endotoxin: <0.1ng/ug AA Sequence: ADP-SRKTYTLTDY LKNTYRLKLYSLR WISDHEYLYKQE |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Dipeptidylpeptidase IV, Recombinant, Human, aa39-766, His-Tag (CD26, ADABP, ADCP2, DPPIV, TP103, DPP4, Dipeptidyl Peptidase 4, Dipeptidyl Peptidase IV, DPP IV, T-cell Activation Antigen CD26, Adenosine Deaminase Complexing Protein 2, CD26 antigen) |
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| Gene, Accession, CAS # | DPP4, Gene ID: 1803, SwissProt: P27487 |
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| Catalog # | 219688 |
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| Order / More Info | Dipeptidylpeptidase IV, Recombinant, Human, aa39-766, His-Tag from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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