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| Product Name | Interleukin-27 p28, Recombinant, Mouse, aa29-234, His-Tag (IL-27 p28, IL-30) |
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| Description | Purity ~90% (SDSPAGE). Interleukin-27 p28, also known as IL30, is a secreted 28kD protein that is considered a member of the IL-6/IL-12 interfamily cytokine family. p28/IL30 is one of several alpha-chain proteins that can associate with various beta-chain proteins to form heterodimeric cytokines in these families. The alphachains (e.g. IL-6, IL-11, Cardiotrophin-1, CLC/CNTF, LIF, Oncostatin M, IL-23 p19, IL27 p28/IL30, IL12/IL35 p35) have a fourhelix bundle structure, while the beta-chains (e.g. EBI3, CLF1, IL12/IL23 p40) resemble class 1 cytokine receptors. These cytokines utilize heteromeric cell surface receptors which contain shared as well as ligand-specific subunits. Divergent biological responses are obtained from the combinatorial association of cytokine subunits and their interaction with various combinations of receptor subunits. Complexity in this system is increased by the generation of soluble receptors and by the competition between proteins for shared subuni |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: Q8K3I6 |
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| Catalog # | 145714 |
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| Order / More Info | Interleukin-27 p28, Recombinant, Mouse, aa29-234, His-Tag (IL-27 p28, IL-30) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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