| 产品详情 |
| Edit |   |
|---|
| Product Name | MMP13 BioAssay™ ELISA Kit, Human |
|---|
| Description | Sandwich ELISA quantitative detection kit for Human MMP13 in cell culture supernates, serum and plasma (heparin). Collagenase 3 is an enzyme that in humans is encoded by the MMP13 gene.[1][2]Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The protein encoded by this gene cleaves type II collagen more efficiently than types I and III. [3] The expression of MMP13 in osteoarthritic cartilage and its activity against type II collagen indicates that the enzyme plays a significant role in cartilage collagen degradation and must, therefore, form part of a complex target for proposed therapeutic interventions based on collagenase inhibition. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Assay Range: 78pg/ml-5000pg/ml Sensitivity: < 5 pg/ml Crossreactivity: There is no detectable cross-r |
|---|
| Size | 96 tests |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | Gene ID: 4322, SwissProt: A8K846 |
|---|
| Catalog # | 143985 |
|---|
| Price | |
|---|
| Order / More Info | MMP13 BioAssay™ ELISA Kit, Human from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|