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| Product Name | Capsaicin Receptor, Rat, Control Peptide |
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| Description | Control Peptide for C1078-01, Capsaicin Receptor, polyclonal antibody. Nociception, the process of detecting noxious chemical, mechanical, or thermal stimuli, occurs predominantly at the peripheral terminal neurons known as polymodal nociceptors. Nociceptors transduce noxious stimuli into membrane depolarization that triggers action potential, conducts the action potential from the sensory sites to the synapses in the CNS, and conversion of action potentials invokes a perception of pain, discomfort, and appropriate mechanical/physical protective reflexes. At the molecular level, nociception is carried out by ion channels or receptors. Capsaicin receptor, termed vanilloid receptor subtype 1 (VR1), has been cloned from sensory neurons. VR1 protein is a heat-gated cation channel that exchanges ~10 Ca+ ions for every Na+ ion resulting into neuronal membrane depolarization and elevated intracellular Ca+ levels. Over-expression of VR1 caused cell death because of continuos influx of Ca+ ions |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | C1078-01E |
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| Order / More Info | Capsaicin Receptor, Rat, Control Peptide from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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