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| Product Name | SM22 alpha, aa1-201, Recombinant, Human |
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| Description | Purity ~85% (SDS-PAGE). TAGLN is a transformation and shape-change sensitive actin cross-linking/gelling protein that belongs to the calponin family. This protein is expressed abundantly in fibroblasts and smooth muscle. It is involved in calcium interactions and contractile properties of the cell that may contribute to replicative senescence. During embryogenesis, TAGLN is expressed in smooth, cardiac and skeletal muscle, but is restricted during late fetal development and adulthood to all vascular and visceral smooth muscle cells and low levels of expression in heart. It is downregulated in several transformed cell lines, indicating that a reduction of TAGLN expression may be an early indicator of the onset of transformation. Source: Recombinant corresponding to aa1-201 of human TAGLN 6x his tagged, expressed in E.coli. AA Sequences: MGSSHHHHHH SSGLVPRGSH MANKGPSYGM SREVQSKIEK KYDEELEERL VEWIIVQCGP DVGRPDRGRL GFQVWLKNGV ILSKLVNSLY PDGSKPVKVP ENPPSMVFKQ MEQVAQFLKA AEDYGVIKTD MFQTVDLFE |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | SM22 alpha, aa1-201, Recombinant, Human (22kD Actin-binding Protein, Protein WS3-10, Smooth Muscle Protein 22-alpha, SM22-alpha, SM22, WS3-10, TAGLN) |
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| Gene, Accession, CAS # | Accession: NP_001001522 |
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| Catalog # | S1014-32 |
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| Order / More Info | SM22 alpha, aa1-201, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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