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| Product Name | Vascular Endothelial Growth Factor 111, Recombinant, Human |
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| Description | Purified ≥ 95%, as determined by SDS-PAGE under reducing conditions and visualized by silver stain. Endotoxin: ≤ 1.0 EU/1ug (LAL). Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult (1-3). It is a member of the PDGF family that is characterized by the presence of eight conserved cysteine residues and a cystine knot structure (4). Humans normally express alternately spliced isoforms of 121, 145, 165, 183, 189, and 206aa in length (4). VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189 (3, 4). Additionally, an active ~18kD form, VEGF111, can be induced in tumor cells by treatment with genotoxic agents and ultraviolet (UV-B) irradiation (5). Like VEGF121, VEGF111 lacks the basic heparin-binding region encoded by exons 6 and 7, and is freely diffusible (4, 5). VEGF111 also lacks major proteolytic cleavage sites enco |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Vascular Endothelial Growth Factor 111, Recombinant, Human (Vascular Endothelial Growth Factor A, VEGFA, VEGF-A, VEG, Vascular Permeability Factor, VPF) |
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| Gene, Accession, CAS # | Accession: ABB58912 |
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| Catalog # | V2110-13G |
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| Order / More Info | Vascular Endothelial Growth Factor 111, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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