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| Product Name | SMAD3, Recombinant, Human |
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| Description | Purity ~ 90% (SDS-PAGE). Purified by using conventional chromatography techniques. SMAD3, also known as mothers against decapentaplegic homolog 3, belongs to the SMAD family of proteins that mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. Small moleucule inhibitors of Smad3 may have tremendous clinical potential in the treatment of pathological fibrotic diseases. Recombinant SMAD3 protein was expressed in E. coli. Source: Recombinant corresponding to aa1-425 of human SMAD3 6x His tagged expressed in E. coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MSSILPFTPP IVKRLLGWKK GEQNGQEEKW CEKAVKSLVK KLKKTGQLDE LEKAITTQNV NTKCITIPRS LDGRLQVSHR KGLPHVIYCR LWRWPDLHSH HELRAMELCE FAFNMKKDEV CVNPYHYQRV ETPVLPPVLV PRHTEIPAEF PPLDDYSHSI PENTNFPAGI EPQSNIPETP PPGYLSEDGE TSDHQMNHSM DAGSPNLSPN PMSPAHNNLD LQPVTYCEPA FWCSISYYEL NQRVGETFHA SQPSMTVDGF TDPSNSERFC LGLLSNVNRN AAVELTRRHI GRGVRLYYIG GEVFAECLSD SAI |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | WB |
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| Other Names | SMAD3, Recombinant, Human (Mothers Against Decapentaplegic Homolog 3, Mothers Against DPP Homolog 3, MAD Homolog 3, Mad3, SMAD Family Member 3, SMAD 3, HSPC193, HsT17436, JV15-2, MADH3, MGC60396) |
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| Gene, Accession, CAS # | Accession: NP_005893 |
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| Catalog # | S1014-53W |
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| Order / More Info | SMAD3, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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