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| Product Name | Interleukin 1 Receptor AcP, Control Peptide (IL1RacP, IL-1 Receptor Accessory Protein) |
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| Description | Peptide corresponding to aa525-540 of human IL-1RAcP, which is identical to those of mouse and rat origins The pro-inflammatory cytokine IL-1 induced cellular response requires two subunits of its receptor, IL-1 receptor I (IL-1RI) and IL-1 receptor accessory protein (IL-1RAcP) (1). IL-1RAcP forms a complex with IL-1RI in response to IL-1 treatment. The IL-1 receptor-associated kinase (IRAK), which mediates activation of NF-kB inducing kinae (NIK) and of NF-kB, recruits to the IL-1R complex through IL-1RAcP (2). IL-1 activation of stress-activated protein kinase and of acid sphingomyelinase also requires IL-1RAcP (3,4). Like IL-1RI, IL-1RAcP subunit is essential for IL-1 mediated cellular response. IL-1RAcP is expressed in many tissues. Applications: Suitable for use as blocking peptide in Western Blot with I5000-05. |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | I5000-05P |
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| Order / More Info | Interleukin 1 Receptor AcP, Control Peptide (IL1RacP, IL-1 Receptor Accessory Protein) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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