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| Product Name | Nogo 1-40, Human |
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| Description | Purity >95% Purified by HPLC. Many tissues such as muscle, skin, liver, and peripheral nerve, have remarkable ability to repair and regrow after injury. However, the CNS (brain and spinal cord) is limited in its ability to repair or regrowth causing permanent brain damage or paralyses. An inhibitory myelin protein, Nogo (Neurite outgrowth), has been cloned and characterized. It may help block the regeneration of the CNS. Nogo is the 4th member of reticulon (Rtn) family. There are three alternative isoforms of Nogo: 1)Nogo-A (full length human protein 1192aa; calculated mol wt 135kD; rat 1163 aa), 2)Nogo-B (373aa; ~37K, lacks186-1004aa within the extracellular domain), and 3)Nogo-C (199aa; ~25 K, similar to rat vp20 and foocen-s; lacks 186-1004aa but which has a smaller, alternative N-terminal domain). Nogo-A has a putative extracellular domain of 1024aa, 2-3 TM domains, and a short C-terminus of 43aa. Nogo-A is localized to the CNS-myelin, and is highly expressed in oligodendorcytes bu |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | ELISA WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | N2116-80 |
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| Order / More Info | Nogo 1-40, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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