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NTF3, Recombinant, Human (NT-3, HDNF, Nerve Growth Factor 2, NGF-2, Neurotrophic Factor, Neurotrophin-3, NTF3) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | NTF3, Recombinant, Human (NT-3, HDNF, Nerve Growth Factor 2, NGF-2, Neurotrophic Factor, Neurotrophin-3, NTF3) |
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| Description | Purity ~95% (SDS-PAGE). NT-3 is found in neurons of the central nervous system. NT-3 is expressed also in muscles and its expression is down-regulated in denervated muscles. Many human gliomas express and secrete NT-3 into the conditioned medium. Some protein domains of NT-3 are identical with those of NGF and BDNF. NT-3 selectively supports the survival of neuronal cell populations. NT-3 has been shown recently to prevent death of cultured embryonic rat spinal motor neurons at picomolar concentrations. NT-3 has been shown to enhance sprouting of corticospinal tract during development and after adult spinal cord lesion. The activities of NT-3 and BDNF are additive in some systems. The biological activities of NT-3 are mediated by a receptor belonging to the trk family of receptors with intrinsic tyrosine-specific protein kinase activity. NT-3 only binds weakly to the trk receptor which is a high-affinity receptor for NGF. Source: Recombinant protein corresponding to human NTF3 expressed in E. coli. Molecular |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: P20783 |
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| Catalog # | 500320 |
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| Order / More Info | NTF3, Recombinant, Human (NT-3, HDNF, Nerve Growth Factor 2, NGF-2, Neurotrophic Factor, Neurotrophin-3, NTF3) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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