| 产品详情 |
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| Product Name | Pertussis Toxin (Islet-Activating Protein) |
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| Description | Five distinct bands when run on 12% SDS-polyacrylamide gels. Pertussis toxin (PT), a virulence factor produced by Bordetella pertussis, is a multi-subunit toxin which binds to most cultured mammalian cells and targets specific G protein, inhibiting the ability of the G protein to function in signaling pathways. Depending on the function of the G protein, the effects of PT can vary. This ability to inhibit pathways utilizing the Gi family of protein-coupled receptors is the basis of the use of PT as a tool in cell biology. PT plays a role in infection by suppressing and modulating various host immune responses to Bordetella pertussis. PT has been used to stimulate experimental autoimmune diseases in rodent models, such as experimental auto immune encephalitis (EAE). Pertussis toxin is a multi-component protein composed of six non-covalently bound subunits ranging in molecular weight from ~9-28kD. These subunits are designated as S1, S2, S3, S4 and S5 and occur in native pertussis toxin |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 215957 |
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| Order / More Info | Pertussis Toxin (Islet-Activating Protein) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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