| 产品详情 |
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| Product Name | Pertussis Toxin (Islet Activating Protein, B. pertussis) |
| Description | Highly Purified (~95%). Pertussis toxin (PT) is a protein-based AB5-type exotoxin produced by the bacterium Bordetella pertussis, which causes whooping cough. PT is involved in the colonization of the respiratory tract and the establishment of infection. PT may have a therapeutic role in treating a number of common human ailments, including hypertension, viral inhibition, and autoimmune inhibition. A large group of bacterial exotoxins are referred to as A/B toxins, in essence because they are formed from two subunits. The A subunit possesses enzyme activity, and is transferred to the host cell following a conformational change in the membrane-bound transport B subunit. Pertussis toxin is an exotoxin with six subunits (named S1 through S5-each complex contains two copies of S4). The subunits are arranged in A-B structure: the A component is enzymatically active and is formed from the S1 subunit, while the B component is the receptor-binding portion and is made up of subunits S2-S5 |
| Size | 50ug |
| Concentration | n/a |
| Applications | ELISA WB |
| Other Names | n/a |
| Gene, Accession, CAS # | n/a |
| Catalog # | 209138 |
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| Order / More Info | Pertussis Toxin (Islet Activating Protein, B. pertussis) from UNITED STATES BIOLOGICAL |
| Product Specific References | n/a |
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