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| Product Name | Umod, Recombinant, Mouse, aa25-588, His-Tag (Uromodulin) |
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| Description | Purity ~90% (SDS-PAGE). Uromodulin: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel-like structure that may play a role in the water barrier permeability. May serve as a receptor for binding and endocytosis of cytokines (IL-1, IL-2) and TNF. Facilitates neutrophil migration across renal epithelia. By similarity Uromodulin, secreted form: In the urine, may contribute to colloid osmotic pressure, retards passage of positively charged electrolytes, prevents urinary tract infection and inhibits formation of liquid containing supersaturated salts and subsequent formation of salt crystals. Source: Recombinant protein corresponding to aa25-588 from mouse Uromodulin, fused to His-Tag at N-terminal, expressed in Yeast. Molecular Weight: ~64.2kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Tamm-Horsfall urinary glycoprotein, THP Cleaved into the following chain, Uromodulin, secreted form |
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| Gene, Accession, CAS # | SwissProt: Q91X17 |
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| Catalog # | 375775 |
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| Order / More Info | Umod, Recombinant, Mouse, aa25-588, His-Tag (Uromodulin) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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