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| Product Name | VEGF165, Recombinant, Rat |
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| Description | Purity ~98% (SDS-PAGE and HPLC). VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothellial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase(flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant rat VEGF is a 38.5kD disulfide-linked homodimeric protein consisting of two 165aa polypeptide chains. Source: Recombinant protein corresponding to rat VEGF165, expressed in E.coli. Biological Activity: Determined by the dose-dependent stimulation of the proliferation of Human umbilical vein endothelial cells (HUVEC). The expected ED50 is 4-8ng/ml. Endotoxin: <0.1ng/ug (1EU/ug) AA Sequence: MAPTT |
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| Size | 2ug, 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | VEGF165, Recombinant, Rat (Vascular Endothelial Growth Factor A Isoform 165A, VEGF 165, VEGF165, VEGF165A, VEGFA) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 149725 |
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| Order / More Info | VEGF165, Recombinant, Rat from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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