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| Product Name | CRK, GST-Tag, Recombinant (CRKII, p38, Adapter Molecule Crk) |
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| Description | Lysate. This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. Source: Partial length protein corresponding to of CRK, fused to GST-Tag at N-terminal, expressed in E. coli. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Molecular Weight: ~38kD |
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| Size | 200ug |
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| Concentration | n/a |
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| Applications | WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | CRK, Gene ID: 1398, Accession: NP_005197, SwissProt: P46108 |
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| Catalog # | 500677 |
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| Order / More Info | CRK, GST-Tag, Recombinant (CRKII, p38, Adapter Molecule Crk) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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