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| Product Name | Glypican 1, Recombinant, Human (Glypiated Proteoglycan 1) |
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| Description | Purity ≥ 95%, as determined by SDS-PAGE under reducing conditions and visualized by silver stain.Endotoxin ≤ 1EU. The Glypicans (glypiated proteoglycans) are a small multigene family of GPI-linked proteoglycans that play a key role in growth factor signaling (1, 2, 3, 4). There are currently six known mammalian Glypicans. They all share a common-sized protein core of 60-70kD, an N-terminus which likely forms a compact globular domain, 14 conserved cysteines that form multiple intrachain disulfide bonds, and a number of C-terminal N- and O-linked carbohydrate attachment sites. Based on exon organization and the location of O-linked glycosylation sites, at least two subfamilies of Glypicans are known, with one subfamily containing Glypicans 1, 2, 4 and 6, and another subfamily containing Glypicans 3 and 5 (3, 5). Human Glypican 1 (GPC-1) is synthesized as a 558 amino acid (aa) preproprecursor that contains a 23 aa signal sequence, a 507 aa mature segment, and a 28 aa C-terminal prosegme |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | ELISA WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: P35052 |
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| Catalog # | G8235-46 |
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| Order / More Info | Glypican 1, Recombinant, Human (Glypiated Proteoglycan 1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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