| 产品详情 |
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| Product Name | Adenosine A2A/A1 Receptor Antagonist |
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| Description | Purity ~97% (HPLC). A blood-brain barrier-permeant indenopyrimidinone that acts as a dual A1/A2A antagonist (Ki = 48.2 and 6.5nM, respectively, against agonist-induced cAMP response in A1- or A2A-expressing CHO-K1 cells) and effectively reverses D2 antagonist haloperidol- (1mg/kg; s.c.) induced catalepsy in both rats and mice (ED50 = 0.3 and <0.1mg/kg, respectively) in vivo by simultaneously reversing A1-mediated inhibition of DA (Dopamine) release and A2A-dependent inhibition of D2 receptor response to DA. Formula: C23H22N4O3 •2HCl Molecular Weight: 475.4 Solubility: DMSO (10mg/ml, clear, yellow solution) |
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| Size | 10mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Adenosine A2A/A1 Receptor Antagonist (2-Amino-8-(2-morpholinoethoxy)-4-phenyl-5H-indeno[1,2-d]-pyrimidin-5-one, diHCl) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217154 |
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| Order / More Info | Adenosine A2A/A1 Receptor Antagonist from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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