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| Product Name | Adenosine A2A Receptor Agonist I, CGS 21680, Hydrochloride |
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| Description | Purity ~98% (HPLC). A xanthin derivative that acts as a potent agonist of adenosine A2A receptors (Ki = 27nM). Exhibits reduced affinity for A2B receptors (Ki = 67nM), but offers greater selectivity over A1R (Ki = 290nM) and A3R (88.8uM). Exerts an anti-inflammatory effect during chronic inflammation and ameliorates the tissue damage associated with collagen-induced arthritis. Also shown to reduce CCR7 Protein Expression in THP1 macrophages. Shown to delay the progressive deterioration of motor performance and prevent a reduction in brain weight in murine model of Huntington's disease. Formula: C23H29N7O6 • HCl Molecular Weight: 536.0 Solubility: DMSO |
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| Size | 5mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Adenosine A2A Receptor Agonist I, CGS 21680, Hydrochloride (CGS-21680, CGS21680, 3-(4-(2-((6-amino-9-((2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxytetrahydrofuran-2-yl)-9H-purin-2-yl)amino)ethyl)phenyl)propanoic Acid) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 217151 |
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| Order / More Info | Adenosine A2A Receptor Agonist I, CGS 21680, Hydrochloride from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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