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| Product Name | PCNA, Recombinant, Human (Proliferating Cell Nuclear Antigen) |
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| Description | Purity ≥95% by SDS-PAGE. Proliferating cell nuclear antigen (PCNA), a protein of 30kD molecular weight also known as cyclin, forms a trimer ring around a DNA double-helix. It binds to a variety of other nuclear proteins and thereby organises biochemical processes at the DNA replication fork. PCNA thereby assumes important functions in DNA synthesis, repair and processing, the regulation of cell cycle and even apoptosis. Anti-PCNA antibodies occur in systemic lupus, where they represent a rare specificity (< 10 % of SLE patients). However, their presence alone or in combination with other autoantibodies should alert the clinician to the presence of defined or evolving SLE. PCNA Human Recombinant produced in SF9 is a glycosylated, polypeptide chain having a molecular mass of 29.7kD. PCNA is expressed with a -6xHis tag and purified by proprietary chromatographic techniques. Immunological Functions: -Binds IgG-type human auto-antibodies. -Standard ELISA test (checkerboard analysis of posit |
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| Size | 5ug, 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | P3115-01C |
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| Order / More Info | PCNA, Recombinant, Human (Proliferating Cell Nuclear Antigen) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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