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| Product Name | GSTA4, Recombinant, Human, aa1-222, His-Tag(Glutathione S-transferase alpha 4, GSTA4-4, GTA4) |
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| Description | Purity ~95% (SDS-PAGE). GSTA4, also known as glutathione S-transferase A4, belongs to the GST superfamily. This enzyme is involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. GSTA4 shows very high activity with reactive carbonyl compounds such as alk-2-enals. GSTA4 is highly effective in catalyzing the conjugate addition of reduced glutathione to 4-hydroxynonenal, an important product of peroxidative degradation of arachidonic acid and a commonly used biomarker for oxidative damage in tissue. This enzyme is expressed at a high level in brain, placenta, and skeletal muscle and much lower in lung and liver. Source: Recombinant protein corresponding to aa1-222 from human GSTA4, fused to His-tag at N-terminal expressed in E. coli. Molecular Weight: ~28.3kD (246aa) Specific Activity: ~4000 pmol/min/ug, and is defined as the amount of enzyme that conjugate 1umole of 1-chloro-2,4- dinitrobenzene (CDNB) with reduced glutathione/minute at pH 6.5 at 25°C. Activ |
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| Size | 20ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_001503 |
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| Catalog # | 351268 |
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| Order / More Info | GSTA4, Recombinant, Human, aa1-222, His-Tag(Glutathione S-transferase alpha 4, GSTA4-4, GTA4) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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