| 产品详情 |
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| Product Name | Histidine Triad Nucleotide-binding Protein 1 Recombinant, Rabbit, aa2-126, His-Tag, Myc-Tag (HINT1) |
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| Description | Purity ~90% (SDS-PAGE). Functions as enzyme, and as scaffolding protein that modulates transcriptional activation by the LEF1/TCF1-CTNNB1 complex and by the complex formed with MITF and CTNNB1. Modulates p53/TP53 levels and p53/TP53-mediated apoptosis. Modulates proteasomal degradation of target proteins by the SCF (SKP2-CUL1-F-box protein) E3 ubiquitin-protein ligase complex (By similarity). Hydrolyzes purine nucleotide phosphoramidates, including adenosine 5'monophosphoramidate (AMP-NH2), adenosine 5'monophosphomorpholidate (AMP-morpholidate) and guanosine 5'monophosphomorpholidate (GMP-morpholidate). Hydrolyzes lysyl-AMP (AMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) generated by lysine tRNA ligase, lysyl-GMP (GMP-N-epsilon-(N-alpha-acetyl lysine methyl ester)) and AMP-N-alanine methyl ester. Can also convert adenosine 5'-O-phosphorothioate and guanosine 5'-O-phosphorothioate to the corresponding nucleoside 5'-O-phosphates with concomitant release of hydrogen sulfide. Source: Recombinant protein corr |
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| Size | 10ug, 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: P80912 |
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| Catalog # | 405946 |
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| Order / More Info | Histidine Triad Nucleotide-binding Protein 1 Recombinant, Rabbit, aa2-126, His-Tag, Myc-Tag (HINT1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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