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| Product Name | IPP-1, aa1-171, Recombinant, Human, His-Tag (Inhibitor of Protein Phosphatase) |
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| Description | Purity ≥ 90% by SDS PAGE. IPP-1, 1-171aa, Human, His-tagged, Recombinant, E. coli Full name: Protein phosphatase inhibitor-1 NCBI Accession: NP_006732 Synonyms: IPP-1, I-1, PPI-1 Protein phosphatase inhibitor-1 (IPP-1) plays an important role in the regulation of glycogen metabolism through inhibition of type-1 protein serine/threonine phosphatase(PP1) activity, and it has been implicated in the regulation of cell growth. IPP-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. In the presence of calcium, PPI-1 is inactivated by calcineurin (or PP2B). Recombinant human IPP-1, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. Molecular Weight: 20kD (179 aa) Sequence: MEQDNSPRKI QFTVPLLEPH LDPEAAEQIR RRRPTPATLV LTSDQSSPEI DEDRIPNPHL KSTLAMSPRQ RKKMTRITPT MKELQMMVEH HLGQQQQGEE PEGAAESTGT QESRPPGIPD TEVESRLGTS GTAKKTAECI PKTHERGSKE PSTKEPSTHI PPLDSKGANS VLEHHHHHH |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | IPP-1, I-1, PPI-1 Protein phosphatase inhibitor-1 (IPP-1) plays an important role in the regulation of glycogen metabolism through inhibition of type-1 protein serine/threonine phosphatase(PP1) activity, and it has been implicated in the regulation of cell growth. IPP-1 activation may impose cAMP control over proteins that are not directly phosphorylated by PKA. In the presence of calcium, PPI-1 is inactivated by calcineurin (or PP2B). Recombinant human IPP-1, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. Molecular Weight: 20kD (179 aa) Sequence: MEQDNSPRKI QFTVPLLEPH LDPEAAEQIR RRRPTPATLV LTSDQSSPEI DEDRIPNPHL KSTLAMSPRQ RKKMTRITPT MKELQMMVEH HLGQQQQGEE PEGAAESTGT QESRPPGIPD TEVESRLGTS GTAKKTAECI PKTHERGSKE PSTKEPSTHI PPLDSKGANS VLEHHHHHH Storage and Stability: May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. |
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| Gene, Accession, CAS # | Accession: NP_006732 |
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| Catalog # | I8465-02B |
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| Order / More Info | IPP-1, aa1-171, Recombinant, Human, His-Tag (Inhibitor of Protein Phosphatase) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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