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| Product Name | ARL6, Recombinant, Human, aa1-186, GST-Tag (ADP-ribosylation Factor-like Protein 6) |
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| Description | Purity ~90% (SDS-PAGE). Involved in membrane protein trafficking at the base of the ciliary organelle. Mediates recruitment onto plasma membrane of the BBSome complex which would constitute a coat complex required for sorting of specific membrane proteins to the primary cilia. Together with BBS1, is necessary for correct trafficking of PKD1 to primary cilia. Together with the BBSome complex and LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regulation. May regulate cilia assembly and disassembly and subsequent ciliary signaling events such as the Wnt signaling cascade. Isoform 2 may be required for proper retinal function and organization. Source: Recombinant protein corresponding to aa1-186 from human ARL6, fused to GST-Tag at N-terminal, expressed in E. coli. Molecular Weight: ~48.0kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Bardet-Biedl syndrome 3 protein |
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| Gene, Accession, CAS # | SwissProt: Q9H0F7 |
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| Catalog # | 372335 |
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| Order / More Info | ARL6, Recombinant, Human, aa1-186, GST-Tag (ADP-ribosylation Factor-like Protein 6) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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