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| Product Name | GSTO1, 140 D, Recombinant, Human |
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| Description | Purified (SDS-PAGE). GSTO1 is a member of the theta class glutathione S-transferase-like (GSTTL) protein family. GSTO1 is expressed in a wide range of human tissues and exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities and also catalyzes the reduction of monomethylarsonate, an intermediate in the pathway of arsenic biotransformation. GSTO1 protects from oxidative stress, a risk factor for Alzheimer disease, vascular dementia and stroke. Several polymorphisms in the coding regions of the human GSTO1 have been identified. A polymorphism causing an alanine-to-aspartate (A140D) substitution in aa140 produces a variant with lowered enzyme activities in the arsenic biotransformation. Source: Recombinant corresponding to aa1-241 from human 140D mutant mature GSTO1, fused to 6x His-tag at N-terminal, expressed in E. coli. Applications: Suitable for use in Western Blot as a control. |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | WB |
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| Other Names | GSTO1, 140 D, Recombinant, Human (GSTTLp28, P28, glutathione S-transferase omega 1-1, glutathione transferase omega, glutathione transferase omega 1, glutathione-S-transferase like, MonomethylArsenous Reductase) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | G8135-21J |
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| Order / More Info | GSTO1, 140 D, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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