| 产品详情 |
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| Antigenic Specificity | CD104 |
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| Clone | UM-A9 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2a, kappa |
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| Format | n/a |
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| Size | 0.02 mg , 0.1 mg , 0.1 mg , 0.2 mg , 0.2 mg |
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| Concentration | n/a |
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| Applications | Biological Blockade, ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), Immunohistology (IH) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD104 (Integrin Beta-4). Recognizes a protein of 205kDa, which is identified as integrin beta-4 (ITGB4). Its epitope is localized in the extracellular domain of ITGB4 protein. Integrins are heterodimers comprised of alpha and beta subunits, that are non-covalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced |
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| Immunogen | Human squamous cell carcinoma (UM-SCC1)Quantity and |
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| Other Names | integrin beta-4 isoform 1; Integrin beta-4; integrin beta-4; GP150; CD104 antigen; integrin beta-4 subunit; integrin, beta 4; GP150; CD_antigen: CD104, ITGB4; ITGB4; CD104 |
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| Gene, Accession # | ITGB4, Gene ID: 3691, NCBI: NP_000204.3, UniProt: P16144 |
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| Catalog # | MBS438251 |
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| Price | |
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| Order / More Info | CD104 Antibody from MYBIOSOURCE INC. |
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| Product Specific References | 1. Signal transduction by the alpha 6 beta 4 integrin: distinct beta 4 subunit sites mediate recruitment of Shc/Grb2 and association with the cytoskeleton of hemidesmosomes. Mainiero F, Pepe A, Wary KK, Spinardi L, Mohammadi M, Schlessinger J, Giancotti FG. EMBO J. 1995;14(18):4470-81. 2. The A9 antigen associated with aggressive human squamous carcinoma is structurally and functionally similar to the newly defined integrin alpha 6 beta 4. Van Waes C, Kozarsky KF, Warren AB, Kidd L, Paugh D, |
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