| 产品详情 |
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| Product Name | SIRT1, Human, BioAssay™ ELISA Kit |
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| Description | Sirtuin 1 is the human ortholog for the yeast Sir2 (silent information regulator 2) protein regulating epigenetic gene silencing as a possible antiaging effect. Sirtuin 1 is an NAD(+)-dependent histone deacetylase, which deacetylate lysines 9 and 14 of histone H3 and lysine-16 of histone H4, involved in various cellular functions such as transcription, energy sensing, and differentiation. Sirtuin1 plays an important role in regulating adipogenesis via repression of PPAR and the gluconeogenic/glycolytic pathways in liver in response to fasting signals through the transcriptional coactivator PGC1A deacetylated at specific lysine residues in an NAD(+)-dependent manner. This assay is a sandwich ELISA for quantitative determination of human Sirtuin 1 in cells. A monoclonal antibody specific for Sirtuin 1 has been precoated onto the 96-well microtiter plate. Standards and samples are pipetted into the wells for binding to the coated antibody. After extensive washing to remove unbound compoun |
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| Size | 100 tests |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | SIRT1, Human, BioAssay™ ELISA Kit (NAD-dependent Protein Deacetylase Sirtuin-1, hSIRT1, Regulatory Protein SIR2 Homolog 1, SIR2-like Protein 1, hSIR2, SIR2L1) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | S1113-81 |
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| Order / More Info | SIRT1, Human, BioAssay™ ELISA Kit from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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