| 产品详情 |
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| Product Name | SIRT2, Human, BioAssay™ ELISA Kit |
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| Description | Sirtuin 2 is a NAD-dependent histone deacetylase (39.5kD) largely localized at the cytoplasm where it is physically associated with microtubules. SIRT2 was found to deacetylate lys40 of alpha-tubulin both in vitro and in vivo and colocalized and interacted in vivo with HDAC6, another tubulin deacetylase. It has been also shown that Sirtuin 2 is a regulator of mitotic progression that acts downstream from CDC14B in a pathway regulating mitotic exit or subsequent cytokinesis. This assay is a sandwich ELISA for quantitative determination of human Sirtuin 2 in cells. A monoclonal antibody specific for Sirtuin 2 has been precoated onto the 96-well microtiter plate. Standards and samples are pipetted into the wells for binding to the coated antibody. After extensive washing to remove unbound compounds, Sirtuin 2 is recognized by the addition of a purified polyclonal antibody specific for Sirtuin 2 (Detection Antibody). After removal of excess polyclonal antibody, HRP conjugated anti-rabbit I |
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| Size | 100 tests |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | SIRT2, Human, BioAssay™ ELISA Kit (NAD-dependent Protein Deacetylase Sirtuin-2, Regulatory Protein SIR2 Homolog 2, SIR2-like Protein 2, SIR2L, SIR2L2) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | S1113-82 |
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| Order / More Info | SIRT2, Human, BioAssay™ ELISA Kit from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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