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| Product Name | S100 Calcium Binding Protein A13, Recombinant, Human (S100A13) |
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| Description | Purity > 97%, as determined by SDS-PAGE and visualized by silver stain. Endotoxin: < 1EU/ug of the protein (LAL). S100A13 is an 11kD member of the S100 (soluble in 100% saturated ammonium sulfate) family of vertebrate EF-hand Ca ++ -binding proteins. It is widely expressed as a homodimer with two 98 amino acid (aa) long subunits. Human S100A13 shares 83%, 90%, 91%, 87%, 78% and 47% aa identity with mouse, rat, cow, dog, opossum and chicken S100A13, respectively. Like other S100 proteins, S100A13 is small and generally acidic, but contains a basic residue-rich sequence at the C terminus, and two EF hand motifs that bind with Ca ++ differing affinities. Some S100 proteins, including S100A13, are able to bind the cell surface receptor for advanced glycation end-products (RAGE). Despite lacking a signal sequence, S100A13 plays an important role in Cu ++ -dependent export of FGF-1 (FGF acidic) and IL-1a from the cell in response to stresses such as heat shock, anoxia and starvation. Bindin |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Accession: NP_005970 |
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| Catalog # | S0051-89 |
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| Order / More Info | S100 Calcium Binding Protein A13, Recombinant, Human (S100A13) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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