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| Product Name | Cadherin T, Recombinant, Human (Truncated Cadherin, Cadherin 13, Heart-Cadherin) |
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| Description | Purity ≥ 90%, by SDSPAGE under reducing conditions and visualized by silver stain. Cadherin13, also known as Tcadherin and Hcadherin, is a 105 kDa member of the cadherin family of transmembrane glycoproteins that mediate calciumdependent intercellular adhesion (1). However, Cadherin13 is an atypical member, lacking transmembrane and cytosolic domains and containing a GPI moiety that anchors Cadherin13 to the plasma membrane (1 2). Human Cadherin13 is synthesized as a 713 amino acid (aa) precursor that contains a 22 aa signal sequence, a 116 aa propeptide, a 555 aa mature chain, and a second propeptide of 20 aa that is removed in the mature form to reveal the GPI anchor (SwissProt # P55290). The mature form contains five cadherin domains and eight potential sites for Nlinked glycosylation. Mature human Cadherin13 shares 96% aa identity with mature mouse Cadherin13. Cadherin13 is expressed in various tissues. It is highly expressed in the heart, and in the CNS, Cadherin13 |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | SwissProt: P55290 |
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| Catalog # | C0108-50F |
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| Order / More Info | Cadherin T, Recombinant, Human (Truncated Cadherin, Cadherin 13, Heart-Cadherin) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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