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| Product Name | MER/MERTK BioAssay™ ELISA Kit, Mouse |
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| Description | Sandwich ELISA quantitative detection kit for Mouse MER/MERTK in cell culture supernates, cell lysates, tissue homogenates and serum. Proto-oncogene tyrosine-protein kinase MER, also called MERTK is an enzyme that in humans is encoded by the MERTK gene. This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. This gene is mapped to 2q13. MERTK signaling plays a role in various processes such as macrophage clearance of apoptotic cells, platelet aggregation, cytoskeleton reorganization and engulfment. Functions in the retinal pigment epithelium (RPE) as a regulator of rod outer segments fragments phagocytosis. This gene also plays an important role in inhibition of Toll-like receptors (TLRs)-mediated innate immune response by activating STAT1, which selectively induces production of suppressors of cytokine signaling SOCS1 a |
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| Size | 96 tests |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | Gene ID: 17289, SwissProt: Q60805 |
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| Catalog # | 143965 |
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| Order / More Info | MER/MERTK BioAssay™ ELISA Kit, Mouse from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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