| 产品名称 |
RCAN3, Recombinant, Human, aa56-241, His-Tag (Calcipressin-3, DSCR1L2, hRCN3, MCIP3, RCN3) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | RCAN3, Recombinant, Human, aa56-241, His-Tag (Calcipressin-3, DSCR1L2, hRCN3, MCIP3, RCN3) |
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| Description | Purity ~90% (SDS-PAGE). Calcipressin-3, also known as RCAN3, is a 241aa protein that potentially is involved in central nervous system development. RCAN3 inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Overexpression of calcipressin-3 results in inhibition of calcineurin activity towards the nuclear factor of activated T-cells (NFAT) transcription factors and also downregulates NFAT-dependent cytokine gene expression in activated Jurkat T-cells. Highest expression occurs in heart, skeletal muscle kidney, liver and peripheral blood leukocytes. Source: Recombinant protein corresponding to aa56-241 from human RCAN3 at N-terminal, fused to His-tag expressed in E.coli. Molecular Weight: ~23.5kD (209aa) AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSEAVFEAR EQKERFEALF TIYDDQVTFQ LFKSFRRVRI NFSKPEAAAR ARIELHETDF NGQKLKLYFA QVQMSGEVRD KSYLLPPQPV KQFLISPPAS PPVGWKQSED AMPVINYDLL CAVSKLGPGE KYELHAGTES TPSVVVHVCE SETEEEEETK NPKQKIAQTR RPDPPTAAL |
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| Size | 50ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 138727 |
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| Order / More Info | RCAN3, Recombinant, Human, aa56-241, His-Tag (Calcipressin-3, DSCR1L2, hRCN3, MCIP3, RCN3) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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