| 产品名称 |
LEP, Recombinant, Human (Leptin, Obese Protein, Obesity Factor, FLJ94114, OB, OBS) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | LEP, Recombinant, Human (Leptin, Obese Protein, Obesity Factor, FLJ94114, OB, OBS) |
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| Description | Purity ≥98% by SDS-PAGE gel and HPLC analyses. Encoded by the ob (obese) gene, Leptin is an adipose-derived cytokine that suppresses appetite and increases thermogenesis. Leptin exerts its anorectic effect via signaling through a hypothalamic receptor termed OB-R. Leptin has been shown to reduce body weight, food consumption, and plasma glucose levels in various in vivo models. Recombinant human Leptin is a 16kD protein containing 147aa residues. Biological Activity: Human Leptin is biologically active in the ob/ob mouse obesity model. The ob/ob mice were treated via intraperitoneal injection once daily at a dose of 5ug Leptin/gm of body weight for 7 days. Significant effects on body weight, food consumption, and plasma glucose levels were observed to saline-treated controls. AA Sequence: MVPIQKVQDD TKTLIKTIVT RINDISHTQS VSSKQKVTGL DFIPGLHPIL TLSKMDQTLA VYQQILTSMP SRNVIQISND LENLRDLLHV LAFSKSCHLP WASGLETLDS LGGVLEASGY STEVVALSRL QGSLQDMLWQ LDLSPGC Crossreactivity: Chicken, Monkey, Mous |
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| Size | 200ug, 1000ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 143423 |
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| Order / More Info | LEP, Recombinant, Human (Leptin, Obese Protein, Obesity Factor, FLJ94114, OB, OBS) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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| 产品资料 |
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