| 产品详情 |
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| Antigenic Specificity | PRESENILIN-1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | monkey |
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| Isotype | n/a |
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| Format | n/a |
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| Size | 0.1 mL |
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| Concentration | n/a |
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| Applications | Immunohistology Frozen, Immunoprecipitation (IP), Western Blot (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | RABBIT ANTI HUMAN PRESENILIN-1 (LOOP). This item recognises presenilin-1 (PSEN1), an integral membrane protein that is widely expressed, especially in brain tissue.PSEN1 is an essential component of the gamma-secretase complex, along with APH-1 (APH-1A or APH-1B), PSEN2, Pen-2 (PEN2), and nicastrin (NCSTN). This endoprotease complex plays a vital role in the evolutionarily conserved Notch signaling pathway, by catalyzing the intramembrane S3 cleavage of ligand-activated Notch receptor proteins ( |
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| Immunogen | n/a |
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| Other Names | presenilin-1 isoform I-467; Presenilin-1; presenilin-1; presenilin 1; Protein S182Cleaved into the following 3 chains:Presenilin-1 NTF subunit; Presenilin-1 CTF subunit; Presenilin-1 CTF12; PS1-CTF12, PSEN1; PSEN1; AD3; FAD; PS1; PS-1; S182; AD3; PS1; PSNL1; PS-1; PS1-CTF12 |
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| Gene, Accession # | Gene ID: 5663, NCBI: NP_000012.1, UniProt: P49768 |
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| Catalog # | MBS222455 |
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| Price | |
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| Order / More Info | PRESENILIN-1 Antibody from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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