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| Product Name | Caspase Family Group I, Active, Recombinant Set (Caspases-1,4,5) |
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| Description | Caspase family proteases play an important role in apoptosis. Currently, the family consists of more than 10 members. Based on their extended substrate specificities, these enzymes were divided into three major groups: Group I (contains caspase-1,-4,-5) Group II (contains caspase-2,-3,-7) Group III (contains caspase-6,-8,-9,-10) Evidences have suggested that Group I caspases are involved primarily in the production of inflammatory cytokines, while group II and III enzymes function in apoptosis as effectors and upstream activators, respectively. Active recombinant human caspases were expressed in E. coli and routinely tested for their ability to enzymatically cleave the substrate YVAD-pNA (for caspase-1), WEHD-pNA (for caspase-4 & -5), VEID-pNA (for caspase-6), IETD-pNA (for caspase-8 & -10) LEHD-pNA (for caspase-9), respectively. Highly active recombinant human caspases were expressed in E. coli and purified. Active recombinant caspases are useful in screening caspase inhibitors, study |
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| Size | 3x25U |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | C2086-10J |
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| Order / More Info | Caspase Family Group I, Active, Recombinant Set (Caspases-1,4,5) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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