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| Antigenic Specificity | CD22 / BL-CAM |
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| Clone | MYG13 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat |
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| Isotype | IgG1, kappa |
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| Format | Protein A/G purified |
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| Size | 0.02 mg , 7 ml , 0.1 mg , 0.1 mg , 0.2 mg |
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| Concentration | n/a |
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| Applications | Functional Studies, Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD22 / BL-CAM Mouse Monoclonal Antibody . Recognizes a protein of 130-140kDa, identified as CD22 (also known as BL-CAM). CD22 expression is restricted to normal and neoplastic B cells and is absent from other haemopoietic cell types. In B-cell ontogeny, CD22 is first expressed in the cytoplasm of pro-B and pre-B cells, and on the surface as B cells mature to become IgD+. It is not expressed by plasma cells, CD22 is found highly expressed in follicular mantle and marginal zone B-cells, and while |
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| Immunogen | Human Raji cells |
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| Other Names | B-cell receptor CD22 isoform 2; B-cell receptor CD22; B-cell receptor CD22; CD22 molecule; B-lymphocyte cell adhesion molecule; BL-CAM; Sialic acid-binding Ig-like lectin 2; Siglec-2; T-cell surface antigen Leu-14; CD_antigen: CD22, CD22; CD22; SIGLEC2; SIGLEC-2; SIGLEC2; BL-CAM; Siglec-2 |
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| Gene, Accession # | CD22, Gene ID: 933, NCBI: NP_001172028.1, UniProt: P20273 |
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| Catalog # | MBS439152 |
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| Order / More Info | CD22 / BL-CAM Antibody from MYBIOSOURCE INC. |
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| Product Specific References | Knapp, W et al. eds Leukocyte Typing IV, p190-192, Oxford University Press, Oxford, 1989 Schlossman SF et al. eds. Leukocyte Typing V, p523-503, Oxford University Press, Oxford, 1989. Tedder TF et al. CD22, a B lymphocyte-specific adhesion molecule that regulates antigen receptor signaling. Annu Rev Immunol 15:481-504. Cyster JG and Goodnow CC. Tuning antigen receptor signaling by CD22: integrating cues from antigens and the microenvironment. Immunity 1997,6:509-517. Tuscano JM et al. Involvemen |
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