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| Product Name | Histone H2B (F2B), Slightly Lysine Rich |
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| Description | Autoantibodies to histone antigens have been described in patients with idiopathic and drug-induced SLE, rheumatoid arthritis, and other conditions. The presence of autoantibodies to histones are frequently found in several rheumatic disorders (1). In one study, the predominant responses to histones in SLE sera were to H1, H2b, and H3. Marked elevations of binding occurred to H1 and H2b in 33% of patients, while 25% showed higher binding to H3 (2). The same study showed the highest anti-histone reactivity to be in patients with rheumatoid arthritis with vasculitis, while the highest reactivity in SLE sera was in those patients with a history of photosensitivity (3). In diploid eukaryotic cells, the chromatin fibers are about 20nM in diameter. They consist of two major components in equal amounts, DNA and basic proteins called histones. The histones are a group of water and dilute acid soluble basic proteins found associated with DNA in chromosomes. They are characterized by relatively |
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| Size | 10mg, 25mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Calf thymus |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | H5110-09 |
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| Order / More Info | Histone H2B (F2B), Slightly Lysine Rich from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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