| 产品详情 |
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| Antigenic Specificity | NCC |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | guinea pig, hamster |
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| Isotype | n/a |
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| Format | peptide affinity purified |
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| Size | 0.1 mL |
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| Concentration | n/a |
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| Applications | Western Blot (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Anti-Phospho-Thr53 NCC Antibody. Specificity: Specific for endogenous levels of the ~160 kDa NCC protein phosphorylated at Thr53. Band of interest smearing likely due to glycosylation. Immunolabeling is completely eliminated by treatment with l-Ptase. |
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| Immunogen | Synthetic phospho-peptide corresponding to amino acid residues surrounding Thr53 conjugated to KLH |
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| Other Names | solute carrier family 12 member 3 isoform 1; Solute carrier family 12 member 3; solute carrier family 12 member 3; solute carrier family 12, member 3; Na-Cl symporter; Thiazide-sensitive sodium-chloride cotransporter, Slc12a3; Slc12a3; NCC; TSC; NCCT; AI035291; Ncc; Tsc |
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| Gene, Accession # | NCC, Gene ID: 20497, NCBI: NP_001192240.1, UniProt: P59158 |
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| Catalog # | MBS500073 |
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| Price | |
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| Order / More Info | NCC Antibody from MYBIOSOURCE INC. |
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| Product Specific References | Feng X, Zhang Y, Shao N, Wang Y, Zhuang Z, Wu P, Lee MJ, Liu Y, Wang X, Zhuang J, Delpire E, Gu D, Cai H. (2015) Aldosterone modulates thiazide-sensitive sodium chloride cotransporter abundance via DUSP6-mediated ERK1/2 signaling pathway. Am J Physiol Renal Physiol. 308(10):F1119-27 Rosenbaek LL, Kortenoeven ML, Aroankins TS, Fenton RA. (2014) Phosphorylation decreases ubiquitylation of the thiazide-sensitive cotransporter NCC and subsequent clathrin-mediated endocytosis. J Biol Chem. 289(19) |
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