| 产品详情 |
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| Antigenic Specificity | MeCP2 (Ser421) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse |
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| Isotype | n/a |
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| Format | peptide affinity purified |
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| Size | 0.1 mL |
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| Concentration | n/a |
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| Applications | Western Blot (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Anti-Phospho-Ser421 Methyl-CpG Binding Protein 2 (MeCP2). Specificity: Specific for the ~55 kDa truncated MeCP2 protein phosphorylated at Ser421. Immunolabeling of the MeCP2 band is blocked by preadsorption with the phospho-peptide used as antigen but not by the corresponding dephospho-peptide. |
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| Immunogen | Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser421 conjugated to KLH Immunogen Species: Mouse |
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| Other Names | methyl-CpG-binding protein 2 isoform 1; Methyl-CpG-binding protein 2; methyl-CpG-binding protein 2; meCp-2 protein; methyl CpG binding protein 2, Mecp2; Mecp2; Mbd5; WBP10; BB130002; 1500041B07Rik; D630021H01Rik; MeCp-2 protein; MeCp2 |
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| Gene, Accession # | MECP2, Gene ID: 17257, NCBI: NP_001075448.1, UniProt: Q9Z2D6 |
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| Catalog # | MBS502181 |
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| Price | |
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| Order / More Info | MeCP2 (Ser421) Antibody from MYBIOSOURCE INC. |
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| Product Specific References | • Amir RE, Van den Veyver IB, Wan M, Tran CQ, Francke U, Zoghbi HY (1999) Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2. Nat Genet. Oct;23(2):185-8. • Hutchinson AN, Deng JV, Cohen S, West AE (2012) Phosphorylation of MeCP2 at Ser421 contributes to chronic antidepressant action. Journal of Neuroscience. Oct 10;32(41):14355-63. • Nan X, Ng HH, Johnson CA, Laherty CD, Turner BM, Eisenman RN, Bird A (1998) Transcrip |
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