| 产品名称 |
Leptin, Recombinant, Human (LEP, FLJ94114, Obese Protein, Obesity Factor, OB, OBS) from UNITED STATES BIOLOGICAL |
| 产品详情 |
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| Product Name | Leptin, Recombinant, Human (LEP, FLJ94114, Obese Protein, Obesity Factor, OB, OBS) |
| Description | Purity ~98% (SDS-PAGE and HPLC). Encoded by the ob (obese) gene, Leptin is an adipose-derived cytokine that suppresses appetite and increases thermogenesis. Leptin exerts its anorectic effect via signaling through a hypothalamic receptor termed OB-R. Leptin has been shown to reduce body weight, food consumption, and plasma glucose levels in various in vivo models. Recombinant human Leptin is a 16kD protein containing 147aa. Source: Recombinant protein corresponding to human Leptin, expressed in E.coli. Biological Activity: Human Leptin is biologically active in the ob/ob mouse obesity model. The ob/ob mice were treated via intraperitoneal injection once daily at a dose of 5ug Leptin/gm of body weight for 7 days. Significant effects on body weight, food consumption, and plasma glucose levels were observed to saline-treated controls. Endotoxin: <0.1ng/ug (1EU/ug) AA Sequence: MVPIQKVQDD TKTLIKTIVT RINDISHTQS VSSKQKVTGL DFIPGLHPIL TLSKMDQTLA VYQQILTSMP SRNVIQISND LENLRDLLHV LAFSKSCHLP WAS |
| Size | 200ug, 1mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | n/a |
| Gene, Accession, CAS # | n/a |
| Catalog # | 149646 |
| Price | |
| Order / More Info | Leptin, Recombinant, Human (LEP, FLJ94114, Obese Protein, Obesity Factor, OB, OBS) from UNITED STATES BIOLOGICAL |
| Product Specific References | n/a |
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