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| Product Name | Leptin, Recombinant, Mouse (Ob, Obese Protein, Obesity Factor) |
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| Description | Purity ≥ 95% by SDS-PAGE and HPLC. Endotoxin: ≤ 0.1ng/ug. Leptin (Anti-Obesity Protein) is the protein product of the ob (obese) gene in mice and seems to be involved in appetite control. The ob gene is expressed in adipose tissue and is thought to regulate the body's fat stores. Mice with the ob/ob genotype also develop a form of diabetes similar to type II (non-insulin dependent) diabetes. Recombinant murine leptin is a 16.2kD protein containing 147 amino acid residues. Biological Activity: Murine leptin has been shown to be biologically active in two different mouse obesity models, ob/ob and NZO. Both strains of mice were treated via intraperitoneal injection once daily at a dose of 5ug leptin/g of body weight for 7 days. Significant effects on body weight, food consumption and plasma glucose levels were observed compared to saline-treated controls. Amino Acid Sequence: MVPIQKVQDD TKTLIKTIVT RINDISHTQS VSAKQRVTGL DFIPGLHPIL SLSKMDQTLA VYQQVLTSLP SQNVLQIAND LENLRDLLHL LAFSKSCSLP QTSG |
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| Size | 200ug, 1000ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | L1670-10 |
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| Order / More Info | Leptin, Recombinant, Mouse (Ob, Obese Protein, Obesity Factor) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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