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| Product Name | Active Rac-GEF Assay Kit (Tiam1) |
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| Description | Background: Small GTP-binding proteins (or GTPases) are a family of proteins that serve as molecular regulators in signal transduction pathways. Rac, a 21 kDa protein, belongs to the family of Rho GTPases regulating a variety of biological response pathways that include cell motility, cell division, gene transcription, and cell transformation. Like other small GTPases, Rac influences molecular events by cycling between an inactive GDP-bound form and an active GTP-bound form. Cycling between the |
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| Size | 20 assays |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | MBS169137 |
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| Order / More Info | Active Rac-GEF Assay Kit (Tiam1) from MYBIOSOURCE INC. |
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| Product Specific References | 1. Arthur, W.T., Ellerbroek, S.M., Der, C.J., and Burridge K. (2002) J. Biol. Chem. 277, 42964-429722. Garcia-Mata R., Wennerberg, K., Arthur, W.T., Noren, N.K., Ellenbroek, S.M., and Burridge K. (2006) Methods Enzymol. 406, 425-437.3. Habets, G.G., Scholtes, E.H., Zuydgeest, D., van der Kammen, R.A., Stam, J.C., Berns, A. and Collard, J.G. (1994) Cell. 77, 537-549.1. Oubaha, M. et al. (2012). Formation of a PKC/beta-Catenin Complex in Endothelial Cells Promotes Angiopoietin-1-Induced Collective Directional Migration and Angiogenic Sprouting. Blood. 120: 3371-3381. |
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