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| Product Name | Tissue Plasminogen Activator, Recombinant, Human (TPA, PLAT) |
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| Description | Purity ~98% (RP-HPLC, SDS-PAGE). Tissue plasminogen activator (abbreviated PLAT or tPA) is a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Plasminogen is synthesized as a single chain which is cleaved by PLAT into the two chain disulfide linked plasmin. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Source: Recombinant protein corresponding to human TPA, a single, glycosylated polypeptide chain containing 527aa, expressed in CHO cells. Molecular Weight: ~59kD Enzymatic Activity: ~580,000IU/mg |
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| Size | 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 209243 |
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| Order / More Info | Tissue Plasminogen Activator, Recombinant, Human (TPA, PLAT) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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