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| Product Name | CDC37, Recombinant, Human (CD10) |
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| Description | Purity ~95% (SDS-PAGE). CDC37 is an essential protein in Saccharomyces cerevisiae and is a molecular chaperone with precise function in cell signal transduction. CDC37 forms a complex/associates with Hsp90 molecular chaperone as one of several auxiliary proteins that are collectively referred to as Hsp90 co-chaperones. CDC37 also forms complex with a number of protein kinases such as CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. CDC34 is involved in directing Hsp90 to its target kinases. CDC37 up-regulation is a common early event in some localized human cancers. CDC37 is necessary for maintaining prostate tumor cell growth and represents a novel target in the exploration for multitargeted therapies. CDC37 plays a role in regulating Hsp90 ATPase activity. Source: Recombinant protein corresponding to human CDC37, a single, non-glycosylated polypeptide chain containing 378aa, expressed in E. coli. Molecular Weight: ~44.4kD |
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| Size | 2ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 208787 |
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| Order / More Info | CDC37, Recombinant, Human (CD10) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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