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| Product Name | HBXIP, Recombinant, Human, aa1-91, GST-Tag (Hepatitis B Virus X-interacting Protein) |
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| Description | Purity ~90% (SDS-PAGE). As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. When complexed to BIRC5, interferes with apoptosome assembly, preventing recruitment of pro-caspase-9 to oligomerized APAF1, thereby selectively suppressing apoptosis initiated via the mitochondrial/cytochrome c pathway. Down-regulates hepatitis B virus (HBV) replication. Source: Recombinant protein corresponding to aa1-91 from human HBXIP, fused to GST-Tag at N-terminal expressed in E. coli. Molecular Weight: ~36.6kD AA |
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| Size | 10ug, 50ug, 100ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Hepatitis B virus X-interacting protein |
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| Gene, Accession, CAS # | SwissProt: O43504 |
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| Catalog # | 373596 |
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| Order / More Info | HBXIP, Recombinant, Human, aa1-91, GST-Tag (Hepatitis B Virus X-interacting Protein) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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