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| Product Name | HDAC1, Active, Recombinant, P. Falciparum, His-FLAG-Tag (Histone Deacetylase 1, RPD3L1) |
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| Description | Purified (~58%). Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. HDAC1 belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. Source: Recombinant corresponding to aa1-450 from Plasmodium falciparum HDAC, fused to Flag-His-tag at C-terminal, expressed in a Baculovirus infected Sf9 cell expression system. Molecular Weight: ~53.4kD Applications: Suitable for use in the study of enzyme kinetics, screening inhibitors, and selectivity profiling. |
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| Size | 20ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 137276 |
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| Order / More Info | HDAC1, Active, Recombinant, P. Falciparum, His-FLAG-Tag (Histone Deacetylase 1, RPD3L1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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