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| Product Name | NFATC1 Recombinant protein |
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| Description | MW: ~125 kDa. Recombinant full-length human NFATC1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: NFATC1 is a member of the NFAT family of proteins which are Ca2+/calcineurin-responsive transcription factors primarily recognized for their central roles in T lymphocyte activation and cardiac valve development (1). NFAT consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T-c |
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| Size | 0.02 mg, 0.05 mg |
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| Concentration | n/a |
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| Applications | Western Blot (WB) |
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| Other Names | [NF-ATC; NFATc; NFAT2; MGC138448] |
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| Gene, Accession, CAS # | NFATC1, Gene ID: 4772, Accession: NP_765978.1 |
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| Catalog # | MBS515224 |
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| Order / More Info | NFATC1 Recombinant protein from MYBIOSOURCE INC. |
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| Product Specific References | 1. Buchholz, M. et al: Overexpression of c-myc in pancreatic cancer caused by ectopic activation of NFATc1 and the Ca2 /calcineurin signaling pathway. EMBO. J. 2006; 25(15):3714-24. 2. Jhun, B.S. et al: Inhibition of AMP-activated protein kinase suppresses IL-2 expression through down-regulation of NF-AT and AP-1 activation in Jurkat T cells. Biochem. Biophys. Res. Commun. 2006; 351(4):986-92. |
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