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| Product Name | Recombinant Mouse SAM domain and HD domain-containing protein 1 |
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| Description | 395-626aa; Partial. MW: 30.7kD. Purity >90% as determined by SDS-PAGE. Host restriction nuclease that blocks early-stage virus replication in dendritic and other myeloid cells. Likewise, suppresses LINE-1 retrotransposon activity. May function by reducing the cellular dNTP levels to levels too low for retroviral reverse transcription to occur. May play a role in mediating proinflammatory responses to TNF-alpha signaling. |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Interferon-gamma-inducible protein Mg11SAM domain and HD domain-containing protein 1] |
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| Gene, Accession, CAS # | SAMHD1, Gene ID: 56045, Accession: NP_001132992.1 |
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| Catalog # | MBS1265404 |
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| Order / More Info | Recombinant Mouse SAM domain and HD domain-containing protein 1 from MYBIOSOURCE INC. |
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| Product Specific References | Cloning and characterization of a novel cDNA that is IFN-gamma-induced in mouse peritoneal macrophages and encodes a putative GTP-binding protein.Lafuse W.P., Brown D., Castle L., Zwilling B.S.J. Leukoc. Biol. 57:477-483(1995) Lineage-specific biology revealed by a finished genome assembly of the mouse.Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., |
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