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| Product Name | Recombinant Human Protein phosphatase 1B |
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| Description | 2-192aa; Full Length of Isoform Beta-X. MW: 36.74kD. Purity >90% as determined by SDS-PAGE. Enzyme with a broad specificity. Dephosphorylates CDK2 and CDK6 in vitro. Dephosphorylates PRKAA1 and PRKAA2. Inhibits TBK1-mediated antiviral signaling by dephosphorylating it at 'Ser-172'. Plays an important role in the termination of TNF-alpha-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB. |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.05 mg (Yeast) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Protein phosphatase 2; C isoform beta; PP2; C-beta] |
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| Gene, Accession, CAS # | PPM1B, Gene ID: 5495, Accession: NP_001028729.1 |
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| Catalog # | MBS1173136 |
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| Order / More Info | Recombinant Human Protein phosphatase 1B from MYBIOSOURCE INC. |
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| Product Specific References | The cloning expression and tissue distribution of human PP2Cbeta.Marely A.E., Kline A., Crabtree G., Sullivan J.E., Beri R.K.FEBS Lett. 431:121-124(1998) Dephosphorylation of human cyclin-dependent kinases by protein phosphatase type 2Calpha and beta2 isoforms.Cheng A., Kaldis P., Solomon M.J.J. Biol. Chem. 275:34744-34749(2000) Protein phosphatase 1B. Cloning and characterization of two major transcripts generated by alternative use of 3' exons.Seroussi E., Shani N., Hayut A., Faier S., Ben-Mei |
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